Product Name: p-Diisopropylbenzene
Chemical Name: 1,4-Diisopropylbenzene
Synonyms: p-DIPB, para-Diisopropylbenzene
CAS Number: 100-18-5
Molecular Formula: C12H18
Recommended Use: Used as an intermediate in organic synthesis, manufacturing of antioxidants, resins, and specialty chemicals
Supplier Information: Contact details of local distributor or producer
Emergency Contact: Local emergency services or poison control center
UN Number: 3077
GHS Classification: Flammable Liquid (Category 3), Acute Toxicity (Category 4, Oral), Skin Irritation (Category 2), Eye Irritation (Category 2A), Aquatic Chronic (Category 2)
Signal Word: Warning
Hazard Statements: Liquid and vapor are flammable. Harmful if swallowed. Causes skin and eye irritation. May cause long-term adverse effects in aquatic environments.
Pictograms: Flame, Exclamation Mark, Environment
Precautionary Statements: Avoid contact with skin and eyes. Prevent release into the environment. Keep away from ignition sources. Use personal protective equipment as required.
Other Hazards: Vapors may accumulate in low or confined spaces, presenting a fire and explosion hazard.
Chemical Name: 1,4-Diisopropylbenzene
Concentration: ≥ 98%
CAS Number: 100-18-5
Impurities and Stabilizing Additives: Minor isomers and synthesis residues may be present at low levels.
Other Components: None of significance identified for hazard classification.
General Advice: Move affected person to fresh air. Remove contaminated clothing.
Inhalation: Move the person to a location with fresh air immediately. Seek medical attention if symptoms like dizziness, nausea, or headache occur.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing and shoes. Get medical attention if irritation develops.
Eye Contact: Rinse eyes cautiously with water for several minutes. Remove contact lenses if possible. Continue rinsing. Get medical attention if irritation persists.
Ingestion: Rinse mouth with water. Do not induce vomiting. Call poison control or seek medical help right away.
Most Important Symptoms: Irritation of skin, eyes, and mucous membranes; respiratory discomfort; nausea; headache.
Suitable Extinguishing Media: Use dry chemical powder, foam, or carbon dioxide. For large fires, use water spray or alcohol-resistant foam.
Unsuitable Extinguishing Media: Avoid using straight water streams as they may spread fire.
Specific Hazards: Vapor can form explosive mixtures with air. Containers may rupture due to pressure buildup when exposed to fire.
Special Protective Equipment for Firefighters: Wear a self-contained breathing apparatus and full protective gear to prevent contact with vapors, fumes, or combustion products.
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, unidentified organic compounds.
Personal Precautions: Evacuate area; ensure adequate ventilation. Keep away sources of ignition. Avoid breathing vapors or mist. Wear suitable protective equipment.
Environmental Precautions: Prevent entry into sewers, waterways, or soil. Notify proper authorities if spill occurs.
Methods for Containment and Cleaning Up: Use inert absorbent material like sand or earth to contain spill. Collect spilled material into containers for disposal. Decontaminate area with detergent and water. Dispose in accordance with local, regional, and national regulations.
Safe Handling Practices: Work in a well-ventilated area. Avoid inhaling vapors and contact with skin and eyes. Keep containers tightly closed. Ground and bond containers during transfer.
Storage Conditions: Store in cool, dry, and well-ventilated area, away from sources of heat, ignition, and incompatible substances such as strong oxidizers.
Storage Temperature: Maintain below 25°C for extended shelf life.
Packaging Material: Use chemical-resistant, tightly sealed containers labeled according to regulations.
Specific Uses: For industrial or laboratory use only.
Exposure Limits: No specific OSHA, ACGIH, or NIOSH exposure limits established for p-Diisopropylbenzene. Follow good industrial hygiene.
Engineering Controls: Use local exhaust ventilation or general dilution ventilation to keep airborne concentrations low.
Personal Protective Equipment:
Eye/Face Protection: Safety goggles or face shield
Skin Protection: Chemical-resistant gloves (nitrile or neoprene) and protective clothing
Respiratory Protection: Use a respirator with organic vapor cartridge if ventilation is insufficient
Hygiene Measures: Wash hands and face after handling. Remove contaminated clothing before eating or drinking.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild aromatic
Odor Threshold: Not available
pH: Not applicable
Melting Point: -23°C
Boiling Point: 232°C
Flash Point: 88°C (closed cup)
Evaporation Rate: Not available
Flammability: Flammable liquid
Upper/Lower Flammability or Explosive Limits: Upper: 6.2% / Lower: 0.7% (estimated)
Vapor Pressure: 0.18 mmHg at 25°C
Vapor Density: 5.6 (air = 1)
Relative Density: 0.86 g/cm³ at 20°C
Solubility: Practically insoluble in water; soluble in organic solvents
Partition Coefficient (n-octanol/water): 5.10
Auto-Ignition Temperature: 420°C
Decomposition Temperature: Not determined
Viscosity: Not available
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Will not react under normal use.
Conditions to Avoid: Exposure to heat, sparks, open flames, and other ignition sources. Intense sunlight or ultraviolet light.
Incompatible Materials: Strong oxidizers such as peroxides, nitric acid.
Hazardous Decomposition Products: Produces carbon monoxide, carbon dioxide, and potentially harmful organic compounds during combustion.
Possibility of Hazardous Reactions: Not expected under normal handling or storage.
Acute Toxicity: Oral LD50 (rat): 4900 mg/kg; Skin LD50 (rabbit): 13000 mg/kg
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms of Exposure: May cause irritation of respiratory tract, skin, eyes; dizziness, headache, and nausea may occur with inhalation.
Chronic Effects: Prolonged or repeated skin contact may cause dermatitis.
Carcinogenicity: No evidence indicates that p-Diisopropylbenzene is carcinogenic to humans.
Mutagenicity and Teratogenicity: Limited data; no significant findings in available studies.
Other Health Effects: Sensitization is not commonly reported. Systemic toxicity unlikely at low exposure levels under normal conditions.
Ecotoxicity: Toxic to aquatic organisms, may cause long-term harmful effects in the aquatic environment.
Aquatic Toxicity: LC50 (Fish, 96h): 2.7 mg/L (estimated); EC50 (Daphnia, 48h): 2 mg/L (estimated)
Persistence and Degradability: Not readily biodegradable; may persist in the environment.
Bioaccumulative Potential: High potential due to high partition coefficient (log Kow 5.10).
Mobility in Soil: Limited water solubility; likely to remain in soil and sediments.
Other Adverse Effects: Accumulation in the food chain may occur over time. Responsible handling and disposal reduce environmental impact.
Disposal Methods: Dispose of in accordance with local, regional, and national regulations at approved facilities. Do not pour into drains or waterways.
Contaminated Packaging: Empty containers must be triple-rinsed or otherwise decontaminated before disposal or recycling. Use facilities authorized to process chemical containers.
Special Precautions: Avoid release into the environment during disposal. Spilled and waste material should be collected in sealed, labeled containers.
UN Number: 3077
Proper Shipping Name: Environmentally Hazardous Substance, Liquid, N.O.S. (p-Diisopropylbenzene)
Transport Hazard Class: 9
Packing Group: III
Environmental Hazard: Yes (Marine Pollutant)
Special Precautions for User: Ensure containers are secure. Follow regulations for the transportation of hazardous and environmentally hazardous materials.
Transport by Land (ADR/RID): Regulated
IMDG (Marine Transport): Marine Pollutant; follow regulations for chemical transportation.
IATA (Air Transport): Regulated; packaging must comply with air transport codes.
TSCA Status (USA): Listed
REACH Status (EU): Registered; subject to restrictions under Annex XVII for environmental hazards.
OSHA Hazard Communication: Meets hazard criteria
SARA Title III: Not listed for Section 302, 304, 313
California Prop 65: Substance not listed
WHMIS Classification (Canada): Class B3 (Combustible Liquid), D2B (Toxic material causing other toxic effects)
Other Regulations: Product use and workplace exposure may be governed by local chemical safety regulations; consult relevant authorities for specific site requirements.
